Misuse of antibiotics and antimicrobial drugs that results in microbial adaptation is the main reason for antimicrobial resistance.
One of the biggest threats in modern medicine is bacterial resistance to antimicrobial agents.
When invasive infection of a burn wound is suspected, empirical systemic antimicrobial treatment must be started.
These results are discussed with respect to the mechanism of membrane disruption by antimicrobial peptides.
Most studies on antimicrobial treatment in community acquired pneumonia include only patients in whom the condition has been radiographically confirmed.
Mammals make more than 500 antimicrobial peptides, and their ancestry dates back some 300 million years.
Otherwise, amoxicillin and ampicillin have almost the same spectrum of antimicrobial activity.
Thus, we believe that the discovery of the crystalline phase is an important new development for the field of antimicrobial peptides.
We had only limited data on antimicrobial drug resistance and no information about treatment with antimicrobial drugs and were not able to study this issue.
Some burns units treat difficult wounds such as facial burns by leaving them exposed and applying antimicrobial ointment.
To keep the wound moist, antimicrobial ointment can be applied to the wound or a hydrating topical dressing, such as a hydrogel, can be used.
Consider swabs if adequate antimicrobial therapy seems ineffective.
Resistance to antimicrobial agents enters microbial populations through mutation or immigration.
Antimicrobial resistance has been demonstrated in all classes of antimicrobial agents.
Political interventions and more prestigious research areas seem to have contributed to a prolonged downturn in antimicrobial research after the second world war.
In pregnant women and in community acquired infections, simple antimicrobial drugs like nitrofurantoin might still be useful.
A variety of antimicrobial peptides are present in mammals.
One is that the clinical microbiology laboratory provides summary data on antimicrobial resistance in a facility to concerned clinicians on a regular basis.
General practitioners agreed that over use of antibiotics would lead to the development of antimicrobial resistance.
This solution has no antimicrobial properties and may allow microbial growth.
noun
An antimicrobial substance.
Example sentencesExamples
Suggested dosing adjustments for antimicrobials are provided in the online supplement.
Generally, patients who state they have a ‘sulfa’ allergy are referring to sulfonamide antimicrobials, such as sulfamethoxazole.
The results of this study suggest that substantial opportunities exist to improve the use of prophylactic antimicrobials for patients undergoing major surgical procedures.
Examples of such devices include catheters coated with heparin or an antibiotic agent, bone cements containing antimicrobials, and blood bags containing anticoagulant or preservation agents.
If the patient is in severe pain or is feverish antimicrobials such as metronidazole 200 mg thrice daily for up to five days may be indicated.
The antimicrobials used most frequently are amoxicillin, sulfonamides and cephalosporins.
Treatment typically includes the use of acid suppressive medications along with antimicrobials.
Studies from the United States suggest that treatment with antimicrobials is a risk factor for infection with drug resistant bacteria, and that this interaction may contribute to mortality.
There is no evidence for prescribing combinations of topical steroids and antimicrobials over steroids alone.
A potential added benefit of such a strategy is the ability of natural antimicrobials to act synergistically with other host defense peptides and proteins.
Minimal evidence was found to support local injection of antimicrobials or the addition of alpha blockers to an antimicrobial treatment regimen to improve outcome and limit recurrence.
Another concern linked to the use of antimicrobials in food-producing animals is the potential for development of resistance in human pathogens that are transmitted to humans via animal-derived food.
Conversely, in wealthier countries the overprescription of antibiotics to meet patients' demands and overuse of antimicrobials in food production is adding to the problem.
Vaccines and antimicrobials may need to be stockpiled so that they can be mobilised rapidly and distributed to large numbers of people.
Some antimicrobials are bactericidal whereas others are bacteriostatic.
With antimicrobials our expectation is that the infecting pathogen will be killed, but the myriad normal bacteria are also exposed.
Topical antimicrobials are considered drugs by the FDA and are regulated as such.
Emergency treatment of dental abscess is antimicrobials, analgesics, and drainage of a fluctuant swelling by a dentist
The book contains numerous charts, tables and figures, including chemical structures for most antimicrobials that readers will find very useful.
These bacteria emerged shortly after the use of certain antimicrobials [antibiotics] in agriculture.