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词汇 antisense
释义

Definition of antisense in English:

antisense

adjectiveˈantɪsɛnsˈantēˌsens
Genetics
  • Having a sequence of nucleotides complementary to (and hence capable of binding to) a coding (or sense) sequence, which may be either that of the strand of a DNA double helix which undergoes transcription, or that of a messenger RNA molecule.

    〔遗传〕反意的,反义的

    Example sentencesExamples
    • The sense and antisense RNAs are complimentary and the strands will readily bind together to form a duplex.
    • Both sense and antisense strands were sequenced from tumour samples; only forward strands were sequenced from corresponding normal tissue.
    • Broken arrows indicate starts of sense and antisense transcription.
    • The genotypes were confirmed by sequencing both sense and antisense strands using forward and reverse primers in separate reactions.
    • Such mutants have been generated by chemical mutagenesis, gene disruption, and antisense gene silencing.

Definition of antisense in US English:

antisense

adjectiveˈantēˌsens
Genetics
  • Having a sequence of nucleotides complementary to (and hence capable of binding to) a coding sequence, which may be either that of the strand of a DNA double helix that undergoes transcription, or that of a messenger RNA molecule.

    〔遗传〕反意的,反义的

    Example sentencesExamples
    • Broken arrows indicate starts of sense and antisense transcription.
    • Such mutants have been generated by chemical mutagenesis, gene disruption, and antisense gene silencing.
    • Both sense and antisense strands were sequenced from tumour samples; only forward strands were sequenced from corresponding normal tissue.
    • The genotypes were confirmed by sequencing both sense and antisense strands using forward and reverse primers in separate reactions.
    • The sense and antisense RNAs are complimentary and the strands will readily bind together to form a duplex.
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