A crystalline compound with basic properties, made by condensation of two guanidine molecules.
〔化〕双胍,缩二胍
Chemical formula: NH(C(NH)(NH₂))₂
Example sentencesExamples
Metformin, the only biguanide currently available in the United States, can be used alone or in combination with sulfonylureas.
Metformin, a biguanide and insulin-sensitizing agent, has been used to restore menstrual cyclicity and induce ovulation in PCOS without the use of additional fertility drugs.
Phenformin, another biguanide, was withdrawn from the market after a rate of 40 to 64 cases of lactic acidosis per 100,000 patient-years was reported.
Metformin is the most common type of biguanide. c.
Metformin is a biguanide that improves peripheral tissue sensitivity to insulin but inhibits hepatic glucose formation.