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词汇 bioavailability
释义

Definition of bioavailability in English:

bioavailability

noun
mass nounPhysiology
  • The proportion of a drug or other substance which enters the circulation when introduced into the body and so is able to have an active effect.

    〔生理〕生物药效率,生物利用度

    Example sentencesExamples
    • Systemic bioavailability secondary to lung bioavailability definitely occurs, but the contribution is insignificant.
    • These parameters are influenced by the plasma clearance, volume of distribution and bioavailability of the drug.
    • Clinicians and patients should beware of possible reductions in systemic bioavailability of conventional drugs when taken concomitantly with St John's wort.
    • These effects may profoundly affect the oral bioavailability of drugs.
    • Chapter sixteen has been written from the viewpoint of establishing bioavailability and bioequivalence of drugs and formulations.

Derivatives

  • bioavailable

  • adjective ˌbʌɪəʊəˈveɪləb(ə)lˌbaɪoʊəˈveɪləb(ə)l
    Physiology
    • (of a drug or other substance) entering the circulation when introduced into the body and so able to have an active effect.

      〔生理〕生物药效率,生物利用度

      bioavailable oral antibiotics
      Example sentencesExamples
      • highly bioavailable forms of nutrients
      • It is not surprising that such complex species are not readily bioavailable, and are therefore not toxic.
      • As with other protein products, predigesting proteins facilitate absorption in the gastrointestinal tract, thus making the amino acids more bioavailable.
      • Vancomycin is poorly bioavailable when administered orally, and for systemic infections the intravenous route is used.

Definition of bioavailability in US English:

bioavailability

nounˌbīōˌəvāləˈbilədē
Physiology
  • The proportion of a drug or other substance which enters the circulation when introduced into the body and so is able to have an active effect.

    〔生理〕生物药效率,生物利用度

    Example sentencesExamples
    • Clinicians and patients should beware of possible reductions in systemic bioavailability of conventional drugs when taken concomitantly with St John's wort.
    • Systemic bioavailability secondary to lung bioavailability definitely occurs, but the contribution is insignificant.
    • These effects may profoundly affect the oral bioavailability of drugs.
    • These parameters are influenced by the plasma clearance, volume of distribution and bioavailability of the drug.
    • Chapter sixteen has been written from the viewpoint of establishing bioavailability and bioequivalence of drugs and formulations.
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