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词汇 acentric
释义

Definition of acentric in English:

acentric

adjective eɪˈsɛntrɪk
  • 1Without a centre; not centralized.

    无中心的;不在中心的

    1. 1.1Genetics (of a chromosome) having no centromere.
      〔遗传〕(染色体)无着丝粒的
      Example sentencesExamples
      • In metaphase, chromatid fragments are attached to the homologous area of the sister chromatid while acentric chromosome fragments are apart from their chromosome of origin.
      • This classification method uses anti-kinetochore antibody staining to identify the presence of kinetochore protein associated with the centromeres of chromosomes or its absence from acentric chromosome fragments.
      • Giant cell, fourth mitotic division showing replicated mirror image dicentric chromosomes and acentric fragments (arrows).
      • Micronuclei are acentric chromosome fragments or whole chromosomes that are left behind during mitotic cellular division and appear in the cytoplasm of interphasic cells as small additional nuclei.
      • The analysis of structural aberrations included chromatid and chromosome breaks, appearance of acentric fragments, dicentric chromosomes and chromatid exchanges (tetraradius forms).
      • Other aberrations, such as minutes, acentric rings, dicentrics and exchanges, were rarely seen.
      • Further, the products of crossovers between inverted repeats may lead to dicentric and acentric chromosomes that often cannot be transmitted to the next generation.
      • However, not all acentric chromosomes and dicentric chromosomes/centric rings were converted to MNi and NPB respectively, depending on the dose of radiation.
      • This paper describes an analysis of the frequency of dicentric chromosomes and acentric fragments in 1260 subjects occupationally exposed to X-rays and 241 controls.
      • They are formed by acentric chromosome fragments or whole chromosomes which are not incorporated into daughter nuclei during cell division.
      • A dicentric chromosome plus an acentric fragment were scored as one single aberration.
      • Six structurally acentric chromosomes were generated from the irradiation of Dp 238, supporting the findings of a previous study.
      • Ectopic crossing over causes chromosomal abnormalities, including deletions, translocations, and acentric and dicentric chromosomes.
      • Also excluded are exchanges that would generate dicentric or acentric chromosomes, such as exchanges that may occur between rDNA subunits lying in opposite orientation.
      • The first numeral refers to the chromosome providing the centromere-carrying segment, the second to the chromosome supplying the acentric segment.
      • Micronuclei can arise from acentric chromosome fragments or whole chromosomes that have not been incorporated in the main nuclei at cell division.
      • Micronuclei may originate from an acentric chromosome fragment or whole chromosomes lost from the metaphase plate and provide therefore a measure of both chromosome breakage and chromosome loss.
      • Micronuclei may originate from acentric chromosome fragments or whole chromosomes lagging behind during cell division.
      • Dicentrics, rings, acentric fragments and asymmetrical translocations were recorded separately.
      • These data further support the idea that the observed micronuclei result from preferential exclusion of acentric DNA fragments.
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