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词汇 paracrine
释义

Definition of paracrine in English:

paracrine

adjective ˈparəkrʌɪnˈperəkrən
Physiology
  • Relating to or denoting a hormone which has effect only in the vicinity of the gland secreting it.

    〔生理〕(与)腺周激素(有关)的,旁分泌的

    Example sentencesExamples
    • Numerous studies have examined the role of paracrine interactions within islets and the importance of gap junctions to islet stimulus-secretion coupling.
    • The excitability of DRG neurons may reflect a previously unsuspected chemosensory or paracrine role played by sensory ganglia.
    • Here, we systematically derive discrete models of cell-to-cell communication from a mechanistic description of autocrine and paracrine signaling in epithelial layers.
    • It was suggested that beta-cell cAMP levels in islets are greater than those in dispersed cells due to the paracrine secretion of glucagon by islet a-cells, which was expected to increase release rate and lead to faster bursting.
    • To assess the possible involvement of a paracrine mechanism, normal human keratinocytes were exposed to SSR and culture medium was collected 24 h later.

Origin

1970s: from para-1 'beside' + krinein 'to separate'.

Definition of paracrine in US English:

paracrine

adjectiveˈperəkrən
Physiology
  • Relating to or denoting a hormone which has effect only in the vicinity of the gland secreting it.

    〔生理〕(与)腺周激素(有关)的,旁分泌的

    Example sentencesExamples
    • Numerous studies have examined the role of paracrine interactions within islets and the importance of gap junctions to islet stimulus-secretion coupling.
    • To assess the possible involvement of a paracrine mechanism, normal human keratinocytes were exposed to SSR and culture medium was collected 24 h later.
    • It was suggested that beta-cell cAMP levels in islets are greater than those in dispersed cells due to the paracrine secretion of glucagon by islet a-cells, which was expected to increase release rate and lead to faster bursting.
    • The excitability of DRG neurons may reflect a previously unsuspected chemosensory or paracrine role played by sensory ganglia.
    • Here, we systematically derive discrete models of cell-to-cell communication from a mechanistic description of autocrine and paracrine signaling in epithelial layers.

Origin

1970s: from para- ‘beside’ + krinein ‘to separate’.

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