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词汇 integrin
释义

Definition of integrin in English:

integrin

nounɪnˈtɛɡrɪnˈɪntəɡrɪn
Biochemistry
  • Any of a class of animal transmembrane proteins involved in the adhesion of cells to each other and to their substrate.

    〔生化〕整联蛋白,整合蛋白

    Example sentencesExamples
    • The expression of integrins on the cell surface facilitates adhesion.
    • Understanding the nature of the interaction between the integrin and cell adhesion molecules can aid in the design of potent therapeutics.
    • Transmembrane proteins, such as integrins, anchor cells to the substrate.
    • The elucidation of the fly genome makes it relatively straightforward to generate and study mutations in proteins previously associated with integrins from other systems.
    • This process is coordinately regulated by the spatial and temporal expression of integrins across the cell surface.

Origin

1980s: from integr- in integral + -in1.

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