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词汇 fibrinolysis
释义

Definition of fibrinolysis in English:

fibrinolysis

nounˌfʌɪbrɪˈnɒlɪsɪsˌfɪbrɪˈnɒlɪsɪsˌfībrəˈnäləsəs
mass nounPhysiology
  • The enzymatic breakdown of the fibrin in blood clots.

    〔生理〕血纤维蛋白溶解

    Example sentencesExamples
    • Molecular markers related to hemostasis and fibrinolysis consist of proteins or peptides that indicate an ongoing physiological or abnormal process related to clot formation, thrombosis, vascular damage, or drug effect.
    • It is likely better to consider it as more fibrinolysis than clotting.
    • However, successful fibrinolysis probably depends on drug delivery to the clot, and as blood pressure falls, so reperfusion becomes less likely.
    • This includes the use of erythropoietin, surgical techniques that minimise blood loss, and drugs that inhibit fibrinolysis; greater degrees of anaemia are tolerated, and phlebotomy undertaken for diagnostic testing is minimal.
    • Increasing stomach pH in patients with an acute bleeding peptic ulcer will enhance platelet function and inhibit fibrinolysis, but do these actions result in better patient outcomes?

Derivatives

  • fibrinolytic

  • adjective
    Physiology
    • It inhibits platelet clumping and enhances fibrinolytic activity, therefore, prolonging bleeding and clotting times.
      Example sentencesExamples
      • This literature mainly comprises the variation in genes for blood coagulation factors, inhibitors, fibrinolytic factors and platelet membrane receptors.
      • Urokinase bound to its receptor maintained fibrinolytic activity over 24 hours in the rabbits.
      • Acute infections that alter hemodynamics and fibrinolytic systems can trigger an ischemic event.
      • Hemostasis involves the integration of many procoagulant proteins, natural anticoagulants, fibrinolytic proteins, and platelet surface glycoproteins.

Definition of fibrinolysis in US English:

fibrinolysis

nounˌfībrəˈnäləsəs
Physiology
  • The enzymatic breakdown of the fibrin in blood clots.

    〔生理〕血纤维蛋白溶解

    Example sentencesExamples
    • It is likely better to consider it as more fibrinolysis than clotting.
    • Molecular markers related to hemostasis and fibrinolysis consist of proteins or peptides that indicate an ongoing physiological or abnormal process related to clot formation, thrombosis, vascular damage, or drug effect.
    • This includes the use of erythropoietin, surgical techniques that minimise blood loss, and drugs that inhibit fibrinolysis; greater degrees of anaemia are tolerated, and phlebotomy undertaken for diagnostic testing is minimal.
    • Increasing stomach pH in patients with an acute bleeding peptic ulcer will enhance platelet function and inhibit fibrinolysis, but do these actions result in better patient outcomes?
    • However, successful fibrinolysis probably depends on drug delivery to the clot, and as blood pressure falls, so reperfusion becomes less likely.
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