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词汇 phosphodiester bond
释义

Definition of phosphodiester bond in English:

phosphodiester bond

nounˌfɒsfə(ʊ)dʌɪˈɛstəˌfäsfōdīˈestər ˌbänd
Biochemistry
  • A chemical bond of the kind joining successive sugar molecules in a polynucleotide.

    〔生化〕磷酸二酯键

    Example sentencesExamples
    • DNA ligase and RNA ligase from the bacteriophage T4 catalyze the formation of the phosphodiester bond between two molecules of nucleic acid.
    • Topological problems related to DNA metabolism are solved by a class of enzymes, named DNA topoisomerases, able transiently to break and reseal phosphodiester bonds via the formation of a covalent DNA-protein intermediate.
    • The alteration in size on cleavage of the phosphodiester bond at the 8-oxoguanine is detected by conventional gel electrophoresis and visualization of the P-labelled fragments.
    • Certain glycosylases also have abasic lyase activity, cleaving the phosphodiester bond adjacent to the abasic deoxyribose residue.
    • Ribozymes are molecules of ribonucleic acid that catalyze reactions on the phosphodiester bond of other RNAs.

Definition of phosphodiester bond in US English:

phosphodiester bond

nounˌfäsfōdīˈestər ˌbänd
Biochemistry
  • A chemical bond of the kind joining successive sugar molecules in a polynucleotide.

    〔生化〕磷酸二酯键

    Example sentencesExamples
    • DNA ligase and RNA ligase from the bacteriophage T4 catalyze the formation of the phosphodiester bond between two molecules of nucleic acid.
    • Topological problems related to DNA metabolism are solved by a class of enzymes, named DNA topoisomerases, able transiently to break and reseal phosphodiester bonds via the formation of a covalent DNA-protein intermediate.
    • The alteration in size on cleavage of the phosphodiester bond at the 8-oxoguanine is detected by conventional gel electrophoresis and visualization of the P-labelled fragments.
    • Ribozymes are molecules of ribonucleic acid that catalyze reactions on the phosphodiester bond of other RNAs.
    • Certain glycosylases also have abasic lyase activity, cleaving the phosphodiester bond adjacent to the abasic deoxyribose residue.
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