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词汇 thioridazine
释义

Definition of thioridazine in English:

thioridazine

nounˌθʌɪə(ʊ)rɪˈdeɪziːn-zin
mass nounMedicine
  • A synthetic compound derived from phenothiazine, used as a tranquillizer, chiefly in the treatment of mental illness.

    〔医〕甲硫哒嗪,硫利哒嗪,硫醚嗪

    Example sentencesExamples
    • The Irish Medicines Board has decided to ban the use of the antipsychotic drug thioridazine in children because of fears over cardiac side effects.
    • Chlorpromazine, haloperidol and thioridazine became the standard treatments for schizophrenia.
    • Neurotoxicity has been reported when lithium is combined with haloperidol, thioridazine, chlorpromazine, and fluphenazine.
    • In some cases, patients who experience unacceptable rigidity, akathisia, or dystonia with high potency agents may benefit from a lower potency neuroleptic such as thiothixene or thioridazine.
    • The phenothiazine associated with most deaths was not thioridazine but chlorpromazine.
    • We compared the frequency of cardiac arrest and ventricular arrhythmia associated with different antipsychotic drugs, in particular comparing thioridazine to haloperidol.

Origin

1950s: from thio- + (pipe)rid(ine) + azine.

Definition of thioridazine in US English:

thioridazine

noun-zin
Medicine
  • A synthetic compound derived from phenothiazine, used as a tranquilizer, chiefly in the treatment of mental illness.

    〔医〕甲硫哒嗪,硫利哒嗪,硫醚嗪

    Example sentencesExamples
    • We compared the frequency of cardiac arrest and ventricular arrhythmia associated with different antipsychotic drugs, in particular comparing thioridazine to haloperidol.
    • The Irish Medicines Board has decided to ban the use of the antipsychotic drug thioridazine in children because of fears over cardiac side effects.
    • In some cases, patients who experience unacceptable rigidity, akathisia, or dystonia with high potency agents may benefit from a lower potency neuroleptic such as thiothixene or thioridazine.
    • Neurotoxicity has been reported when lithium is combined with haloperidol, thioridazine, chlorpromazine, and fluphenazine.
    • Chlorpromazine, haloperidol and thioridazine became the standard treatments for schizophrenia.
    • The phenothiazine associated with most deaths was not thioridazine but chlorpromazine.

Origin

1950s: from thio- + ( pipe)rid(ine) + azine.

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