Definition of degranulate in English:

degranulate

verb diːˈɡranjʊleɪtdēˈɡranyəˌlāt

[no object]Physiology

(of a cell) lose or release granules of a substance, typically as part of an immune reaction.
〔生理〕（细胞）脱粒，失粒
the eosinophils degranulate, releasing the toxic contents of the granules
嗜曙红细胞脱粒，释放出颗粒状有毒物质。
Example sentencesExamples
- When mast cells degranulate they release tryptase, in addition to histamine and prostaglandins.
- We found corroborative evidence that neutrophils are stimulated to degranulate and produce reactive oxidants in the airways of children with Cystic Fibrosis.
- IL - 8 also activates neutrophils to degranulate and cause tissue damage.
- Pus is thick because of its high DNA content from degranulated cells.
- It has been demonstrated that DEPs directly degranulate mast cells and increase histamine levels and symptom severity in humans.

Derivatives

degranulation

noun

Physiology

The data from guinea pigs were confirmed in the human system; IL - 8-activated neutrophils stimulated degranulation, and this was inhibited by elastase inhibitors.
Example sentencesExamples
- Mast cell degranulation releases vasoactive substances, including histamine, which sustain the reaction by depositing additional immune complexes.
- Ingestion of certain foods, including strawberries, tomatoes, shrimp, lobster, cheese, spinach, and eggplant, also can trigger hives through direct mast cell degranulation.
- The ‘itch-scratch’ cycle induces mast cell degranulation and cytokines that may respond to antihistamines.
- These cells, along with similar tissue-based cells, have receptors for IgE and participate in the degranulation of white blood cells that occurs during allergic reactions.

Definition of degranulate in US English:

degranulate

verbdēˈɡranyəˌlāt

[no object]Physiology

(of a cell) lose or release granules of a substance, typically as part of an immune reaction.
〔生理〕（细胞）脱粒，失粒
the eosinophils degranulate, releasing the toxic contents of the granules
嗜曙红细胞脱粒，释放出颗粒状有毒物质。
Example sentencesExamples
- We found corroborative evidence that neutrophils are stimulated to degranulate and produce reactive oxidants in the airways of children with Cystic Fibrosis.
- It has been demonstrated that DEPs directly degranulate mast cells and increase histamine levels and symptom severity in humans.
- When mast cells degranulate they release tryptase, in addition to histamine and prostaglandins.
- IL - 8 also activates neutrophils to degranulate and cause tissue damage.
- Pus is thick because of its high DNA content from degranulated cells.

词汇	degranulate
释义	Definition of degranulate in English: degranulate verb diːˈɡranjʊleɪtdēˈɡranyəˌlāt [no object]Physiology (of a cell) lose or release granules of a substance, typically as part of an immune reaction. 〔生理〕（细胞）脱粒，失粒 the eosinophils degranulate, releasing the toxic contents of the granules 嗜曙红细胞脱粒，释放出颗粒状有毒物质。 Example sentencesExamples When mast cells degranulate they release tryptase, in addition to histamine and prostaglandins. We found corroborative evidence that neutrophils are stimulated to degranulate and produce reactive oxidants in the airways of children with Cystic Fibrosis. IL - 8 also activates neutrophils to degranulate and cause tissue damage. Pus is thick because of its high DNA content from degranulated cells. It has been demonstrated that DEPs directly degranulate mast cells and increase histamine levels and symptom severity in humans. Derivatives degranulation noun Physiology The data from guinea pigs were confirmed in the human system; IL - 8-activated neutrophils stimulated degranulation, and this was inhibited by elastase inhibitors. Example sentencesExamples Mast cell degranulation releases vasoactive substances, including histamine, which sustain the reaction by depositing additional immune complexes. Ingestion of certain foods, including strawberries, tomatoes, shrimp, lobster, cheese, spinach, and eggplant, also can trigger hives through direct mast cell degranulation. The ‘itch-scratch’ cycle induces mast cell degranulation and cytokines that may respond to antihistamines. These cells, along with similar tissue-based cells, have receptors for IgE and participate in the degranulation of white blood cells that occurs during allergic reactions. Definition of degranulate in US English: degranulate verbdēˈɡranyəˌlāt [no object]Physiology (of a cell) lose or release granules of a substance, typically as part of an immune reaction. 〔生理〕（细胞）脱粒，失粒 the eosinophils degranulate, releasing the toxic contents of the granules 嗜曙红细胞脱粒，释放出颗粒状有毒物质。 Example sentencesExamples We found corroborative evidence that neutrophils are stimulated to degranulate and produce reactive oxidants in the airways of children with Cystic Fibrosis. It has been demonstrated that DEPs directly degranulate mast cells and increase histamine levels and symptom severity in humans. When mast cells degranulate they release tryptase, in addition to histamine and prostaglandins. IL - 8 also activates neutrophils to degranulate and cause tissue damage. Pus is thick because of its high DNA content from degranulated cells.
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